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Observational pragmatic and naturalistic study to determinate the effectiveness of the switch to vortioxetine (mean dosage 13.11±4.03) in 74 patients aged 43.1 ± 12.65 ( 54% males) at risk of discontinuing treatment due to sexual dysfunction Serotonergic antidepressants are frequently associated with the onset of sexual dysfunction in sexually active patients exceeding 70% The salsex scale was applied at two moments

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Vortioxetine׳s tolerability in the switch population was compared to the overall mdd population. Vortioxetine, which was approved for patients with major depressive disorder (mdd), has a receptor profile that suggests limited impact on sexual functioning. Background antidepressant treatment is related to various sexual dysfunctions

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This may cause discontinuation of the medication

This study aims to evaluate the level of sexual dysfunction of antidepressant users and the possible factors linked Methods demographic variables and sexual dysfunction level of 452 people in total (291 males and 161 females) were assessed by demographic data form. With interest we read the study of baldwin et al Aim to evaluate sexual functioning in healthy volunteers administered vortioxetine compared with paroxetine, an antidepressant known to cause sexual dysfunction, and placebo.