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Sex chromosomes are the genetic elements that define a person's biological sex Understand how these chromosomes influence your biology and health. Learn about the xx and xy chromosomes, the sex determination system, and other chromosome combinations.

In the xx/xy system, karyotypic females usually have two x chromosomes (xx), while karyotypic males usually have a single x and a single y chromosome (xy). Cracking the code to sex and genetics The other 22 pairs of chromosomes are called autosomes

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Individuals having two x chromosomes (xx) are female

Individuals having one x chromosome and one y chromosome (xy) are male The x chromosome resembles a large autosomal chromosome with a long and a short arm The y chromosome has one long arm and a very short second arm. These include 22 pairs of “autosomes” (which refers to all chromosomes that are not sex chromosomes) and a pair of sex chromosomes, either an x and a y (which makes for a male) or two xs (female)

That means the genetic signature for a person with 46 chromosomes is either 46,xy (males), or 46,xx (females). Xx and xy chromosomes are only part of the story Discover how sex chromosomes vary naturally and why biological sex isn't always binary Learn about dsds and intersex variations.